I-10 East remains closed at Tony Lama as police investigate a collision involving three vehicles near I-10 and McRae.
I-10 West was closed for nearly an hour at McRae and traffic heading west backed up to Zaragoza at one point.
I-10 West has reopened.
ABC-7 has learned two cars and a pickup were involved in the wreck. ABC-7 is working to confirm the severity of the injuries suffered by those involved.