However, fellow Republican Sen. John McCain of Arizona rejected Cruz's conclusion and said he believes the Arizona legislature would take another look at what he called the state's "controversial" law.
What are the chances of repeal?
In Florida, Scott's office noted that the task force he appointed recommends the law stay in place, though with minor tweaks, including limiting neighborhood watches to observing and reporting.
Daniel Webster, director of the Johns Hopkins Center for Gun Policy and Research, said he doubted protests against "stand your ground" laws would change anything.
Overturning laws isn't very common, he said, and "stand your ground" laws have some popular appeal due to the "the very general notion that citizens should be able to protect themselves and you shouldn't have to, in essence, run from crime."
Also, Webster noted, the laws are relatively new, with most enacted in the past eight years. Therefore, it was unlikely the same legislators who passed them would suddenly be inclined to think they were wrong, he said.
"The more common response is, they're going to dig their heels," Webster added.
Doubts about 'stand your ground'
According to the National District Attorneys Association, "stand your ground" laws emerged due to "diminished sense of public safety" after 9/11, a lack of confidence in the criminal justice system's ability to protect victims, a perception that due process trumps victims' rights and a decrease in gun legislation.
A study by the group cited concerns from law enforcement officials about such laws, including doubts that they would deter criminals.
Webster pointed to a Texas A&M University study examining crime in more than 20 states that passed some version of "stand your ground" laws from 2000 to 2010. Researchers found that not only was there no decrease in robbery, burglary and aggravated assault, but there was an 8% spike in reported murders and non-negligent manslaughter.